| OUR
LABS |
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Animal Electrophysiology Lab |
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- Cerebral
ischemia/reperfusion and preconditioning in vivo and in vitro
- Kainate induced
epilepsy in rat
- Research
of the effect of anesthetics on the electrical brain activity
- Research
on the functional changes induced by diabetes mellitus on the visual
system
- Normal
and pathological physiology studies of the heart and cardiovascular
system
- Physiopathology
studies on the degenerative mechanisms affecting the acustico-vestibular
system
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| Cellular
Electrophysiology Lab |
|
- Cellular
electrophysiology and neuropharmacology studies in-vitro (on brain
slices or cell cultures) and in vivo (stereotaxy on mouse/rat brain)
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| Human
Electrophysiology Lab |
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- Sleep studies
on human subjects concerning: sleep architecture, study of dreams,
study of memory
- Electroencephalography,
psychophysiology, cognitive functions and neuromarketing studies
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| Cell
Culture Lab |
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- Research
on neuronal cell cultures, neuroprotection and recovery mechanisms,
neuropharmacology
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| Animal
Behaviour Lab |
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- Memory,
learning & behavior studies on rats, development of new animal
models for neurological and pshychiatrical disorders, investigation
of the effects of pharmacological agents.
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| RESEARCH
GRANTS |
| Project
PNCD II nr. 41001/2007, Identification and characterization of brain
cancer biomarkers expressed in serum and CSF through advanced glycomic
methods based on mass spectrometry. (project
webpage)
2006-present,
CEEX Module 3, 242/2006, "The development of a European Network
for the investigation of interneuronal and neuroglial relations in energetic
stress, neurodegenerative diseases and ageing, aiming the development
of new therapeutic strategies". (project
webpage)
2004-2006,
Viasan Project nr. 270/2004, National Research Programme VIASAN, „Study
on the dorsal raphe 5-HT circuites on behavior and sleep. Neuropharmacological
interactions with Nicotine”.
2004-2006, Viasan
Project nr. 269/2004, National Research Programme VIASAN, „Post-ischemic
cortical hiperexcitabilitaty: in-vivo study on rat”.
2003-2006,
Viasan Project nr. 253/2003, National Research Programme VIASAN, „Cellular
and molecular study of the effect of hypoxia on the in-vitro neuronal
development and excitability ”.
2001-2003,
Viasan Project nr. 158/2001, National Research Programme VIASAN, „Molecular
and cellular mecanisms of ischemic cerebral preconditioning”.
|
| RESEARCH
GRANTS WITH THE ROMANIAN ACADEMY OF MEDICAL SCIENCES |
- EEG and Hypoxia
in rat.
- Protective role
of Gingko Biloba in cerebral ischemia in rat.
- 1994–1998,
Project A14/1994, Contract nr. 85 /1994 between M.C.T. (A.N.S.T.I.)
& UMF “Carol Davila”: „Protective effect of
calcium blocking agents in cerebral ischemia.”.
- 1999–2000,
Contract nr. 1285/1996, PROGRAM ORIZONT 2000 between A.N.S.T.I. &
U.M.F. „Carol Davila”, through the following projects:
- A10/1999,
B10/2000 – „Study of the EEG computerised analysis
of Kainic Acid induced experimental epilepsy”.
- A11/1999,
B11/2000 – „Preconditioning mechanisms in global cerebral
ischemia and reperfusion”.
- A8/1999,
B8/2000 – „Cellular mechanisms induced by cerebral
ischemia and reperfusion: Apoptosis, Necrosis, Neuronal survival”.
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| TECHNIQUES |
- Four-vessel
occlusion model for global cerebral ischaemia in rat.
- Focal ischaemia
by MCA occlusion.
- Hypoxia induction
model in rat.
- Stereotaxic
drug administration.
- EEG recording
and computerised EEG analysis in humans and in rats.
- Extra- and Intra-cellular
electrophysiological recordings on brain slices and from in vivo rat
brain.
- In vivo and
in vitro NO detection.
- Enzymatic determination
on rat brain homogenate.
- Chronic electrophysiology
electrodes implant.
- Polisomnographic
recording and analisys in humans and in rats.
- Neuronal cell
cultures.
- Ischemia/Hypoxia
in vitro studies.
- Immunohisto-
and cyto-chemistry techniques.
- Rat behavior
and reaction tests
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